David Vendetta's career as a professional DJ only starts in 2002. At that time, he meets Antoine Clamaran, another popular French DJ, who produces Vendetta's first three maxi singles Fiction – No Sex, She Loves Me – Party People and Alicante – Cleopatra. He also starts working as a producer when American DJ Roger Sanchez asks him to remix some of his songs.[2]

In 2006, Vendetta releases the song Love to love you baby, which samples Donna Summer, and manages to peak at #20 at the French Singles Chart.[3] The follow-up single Unidos para la música even reaches the Top 5 in France and the Top 30 in Belgium-Wallonia.[4]

In addition to his work as a producer, Vendetta also animates a weekly radio show on FG DJ Radio and organizes parties in Ibiza, New York, Moscow, Marrakech and many other cities.[5]

In April 2010, he returned with his second album Vendetta. It includes collaborations with artists such as Haifa Wehbe, Tara McDonald and Alim Qasimov.